About the Calculator

In the United States, more than 80% of tuberculosis (TB) cases are the result of reactivated latent TB infection. Targeted screening and treatment of latent tuberculosis infection (LTBI) in selected populations is endorsed as a cost-effective, necessary step to TB elimination in the U.S.

The following calculator is intended to help clinicians responsible for TB control to optimize resources related to TB prevention. The calculator allows cost comparisons between diagnostic methods and treatment options, while estimating the program costs of screening populations for latent tuberculosis infection (LTBI).

Please enter the estimated number of individuals to be screened for LTBI  


    %
 
Treatment Cost Comparison
  Self-administered Treatment DOPT Treatment
  TST Screening IGRA Screening TST Screening IGRA Screening
Treatment cost per completed treatment        
Total diagnostic and screening cost        
The number of TB cases prevented        
The cost per TB case prevented        
Cost to treat one potential case of active TB  
Total costs to treat all active TB potentially developing from screened population        
Diagnostic Cost Comparison
  TST Screening IGRA Screening
True Positive    
False Positive    
True Negative    
False Negative    
Number needed to screen for 1 true LTBI+ diagnosis    
Cost per completed screen on LTBI+ patient    
Cost per completed screen for LTBI- patient    
Cost per true LTBI diagnosis    
Surveilance Cost Comparison
  TST Screening IGRA Screening
Total surveillance cost    
Total surveillance cost per true positive    
Number of true positives per $1000 of surveillance cost    
Total Program Costs
  Self-administered Treatment DOPT Treatment
  TST Screening IGRA Screening TST Screening IGRA Screening
Total program cost (total surveillance cost + cost to treat all positives)
Total cost to find and treat one infected person 1159.29 2980.18 2907.58 4728.47